Atrioventricular Canal (AV Canal) Defect

Introduction

Atrioventricular canal (AV canal) defect is a congenital heart condition that affects the structure of the heart’s chambers and valves. It is a significant defect that can lead to severe complications if left untreated.

What is AV Canal Defect?

AV canal defect involves a defect in the central part of the heart, where the atria (upper chambers) and ventricles (lower chambers) are not properly separated.

Types of AV Canal Defect:

  • Complete AV Canal Defect: A large hole in the center of the heart involving both atria and ventricles and affecting the valves.
  • Partial AV Canal Defect: A hole between the atria and abnormalities in the mitral valve.

Causes and Risk Factors

The condition is congenital, meaning it is present at birth. It is more commonly seen in babies with genetic conditions like Down syndrome.

Risk Factors:

  • Genetic disorders (e.g., Down syndrome)
  • Maternal illnesses during pregnancy (e.g., rubella, diabetes)
  • Exposure to harmful substances during pregnancy

Symptoms

Symptoms often depend on the severity of the defect and may include: - Difficulty breathing - Poor feeding and slow weight gain - Cyanosis (bluish skin due to lack of oxygen) - Frequent lung infections - Heart murmur (abnormal heart sound detected by a doctor)

Diagnosis

Diagnosis usually involves: - Echocardiogram (ultrasound of the heart) - Electrocardiogram (ECG) - Chest X-ray - Cardiac catheterization (in some cases)

Treatment

  • Surgical repair is the only definitive treatment.
  • Surgery typically involves closing the holes and reconstructing the heart valves.
  • Medications (e.g., diuretics) may be used to manage symptoms before surgery.

Outlook & Long-Term Care

With successful surgery, most children can lead normal lives, but they may need long-term cardiac monitoring.

Conclusion

AV canal defect is a serious congenital heart condition that requires prompt diagnosis and treatment. Advances in surgery have greatly improved outcomes for affected children.

Source recommendations

1. American Heart Association Guidelines

  1. https://professional.heart.org/en/guidelines-and-statements
  2. https://www.heart.org/
  3. https://professional.heart.org/en/guidelines-statements
  4. https://cpr.heart.org/en/resuscitation-science/cpr-and-ecc-guidelines
  5. https://www.heart.org/en/healthy-living/fitness/fitness-basics/aha-recs-for-physical-activity-in-adults

2. European Society of Cardiology Guidelines

  1. https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines
  2. https://academic.oup.com/eurheartj/article/42/34/3227/6358713
  3. https://www.escardio.org/Guidelines
  4. https://academic.oup.com/eurheartj/article/44/39/4043/7238227
  5. https://www.escardio.org/

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