Understanding C-Reactive Protein (CRP) and Cardiac Health

Introduction

C-reactive protein (CRP) is a substance produced by the liver in response to inflammation. It is commonly used as a marker to assess inflammation levels in the body. While CRP is not specific to heart disease, high levels can indicate chronic inflammation, which is linked to cardiovascular problems.

CRP and Heart Disease

Elevated CRP levels have been associated with an increased risk of cardiovascular diseases, including: - Coronary artery disease (CAD) : Inflammation can contribute to the buildup of plaques in arteries, leading to heart attacks. - Atherosclerosis : A condition where arteries become narrowed due to plaque formation. - Stroke : Increased CRP levels have been linked to a higher risk of stroke. - Hypertension (high blood pressure) : Chronic inflammation may contribute to blood vessel damage, worsening hypertension.

High-Sensitivity CRP (hs-CRP) Test

A specialized test known as high-sensitivity CRP (hs-CRP) is used to assess the risk of cardiovascular disease. The risk categories based on hs-CRP levels are: - Low risk : <1.0 mg/L - Intermediate risk : 1.0 - 3.0 mg/L - High risk : >3.0 mg/L

How to Lower CRP Levels

To reduce CRP and improve heart health, consider the following: - Healthy Diet : Increase intake of fruits, vegetables, whole grains, and healthy fats. - Regular Exercise : Physical activity reduces systemic inflammation. - Weight Management : Obesity is linked to higher CRP levels. - Smoking Cessation : Smoking contributes to inflammation and cardiovascular risk. - Managing Chronic Conditions : Treating diabetes, hypertension, and high cholesterol can help lower inflammation.

Conclusion

Checking CRP levels, especially hs-CRP, can provide valuable insights into cardiovascular risk. However, it should not be used alone but rather as part of a comprehensive assessment of heart health.

Source recommendations

1. American Heart Association Guidelines on Inflammatory Markers

1. https://www.ahajournals.org/doi/10.1161/01.cir.0000052939.59093.45
2. https://www.heart.org/en/news/2024/12/31/coffee-may-protect-cognition-in-people-with-afib
3. https://newsroom.heart.org/news/6-common-heart-health-supplements-ineffective-at-lowering-cholesterol-compared-to-statins
4. https://www.heart.org/en/news/2024/03/19/study-offers-insight-on-how-hot-weather-impairs-the-immune-system
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2. European Society of Cardiology Guidelines on Cardiovascular Disease Prevention

1. https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/CVD-Prevention-Guidelines
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