Cardiac Arrest Supportive Therapy

Introduction

Cardiac arrest is a life-threatening condition where the heart suddenly stops beating, leading to an absence of blood circulation. Immediate intervention is crucial to increase the chances of survival. Supportive therapy refers to the ongoing management of the patient after the initial resuscitation efforts, ensuring stabilization and recovery.

Immediate Actions

  • Recognition of Cardiac Arrest: Loss of consciousness, absence of pulse, and lack of normal breathing.
  • Early Cardiopulmonary Resuscitation (CPR): High-quality chest compressions and rescue breathing to maintain circulation and oxygenation.
  • Defibrillation: If the patient has a shockable rhythm (ventricular fibrillation or pulseless ventricular tachycardia), early defibrillation is key.

Post-Resuscitation Supportive Therapy

1. Optimizing Oxygenation and Ventilation

  • Maintain adequate airway and breathing using oxygen supplementation or mechanical ventilation.
  • Avoid hyperoxia (excess oxygen), as it may lead to oxidative damage.
  • Use capnography to monitor end-tidal CO₂, guiding ventilation efforts.

2. Hemodynamic Support

  • Continuous monitoring of blood pressure and cardiac function.
  • Use of intravenous fluids and vasopressors (such as norepinephrine) if needed to support blood pressure.
  • Identifying and treating reversible causes (e.g., hypoxia, acidosis, electrolyte imbalances).

3. Targeted Temperature Management (TTM)

  • Cooling the body to 32–36°C for 24 hours to reduce the risk of neurological damage.
  • Preventing fever after cardiac arrest, as hyperthermia worsens outcomes.

4. Neurological Monitoring and Prognostication

  • Regular neurological exams to assess brain function and potential recovery.
  • Use of EEG (Electroencephalography) to detect seizures.

5. Multidisciplinary Post-ICU Care

  • Cardiac rehabilitation program to aid functional recovery.
  • Screening and management of cognitive and psychological sequelae such as depression and PTSD.

Conclusion

Survivors of cardiac arrest require comprehensive supportive therapy to minimize complications and improve long-term outcomes. A structured, multidisciplinary approach incorporating respiratory, cardiovascular, neurological, and rehabilitation strategies is essential for optimizing recovery.

Source recommendations

1. 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care

  1. https://professional.heart.org/en/science-news/2020-aha-guidelines-for-cpr-and-ecc
  2. https://www.ahajournals.org/doi/10.1161/CIR.0000000000000918
  3. https://cpr.heart.org/en/resuscitation-science/cpr-and-ecc-guidelines
  4. https://pubmed.ncbi.nlm.nih.gov/33081529/
  5. https://publications.aap.org/pediatrics/article/147/Supplement%201/e2020038505E/73495/Part-5-Neonatal-Resuscitation-2020-American-Heart

2. European Resuscitation Council Guidelines 2021

  1. https://cprguidelines.eu/guidelines-2021
  2. https://www.sciencedirect.com/science/article/pii/S0300957221000551
  3. https://cprguidelines.eu/
  4. https://www.sciencedirect.com/science/article/pii/S0300957221000630
  5. https://pubmed.ncbi.nlm.nih.gov/33773835/

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