Chronic Systolic Congestive Heart Failure

Introduction

Chronic systolic congestive heart failure (CHF) is a condition in which the heart's ability to pump blood is weakened. This happens when the left ventricle, which is responsible for pumping oxygen-rich blood to the body, becomes weakened and cannot contract effectively. As a result, less blood is ejected with each heartbeat, leading to symptoms such as fatigue, shortness of breath, and fluid buildup.

Causes

Several conditions can lead to chronic systolic CHF, including: - Coronary artery disease (CAD): Blockages in the coronary arteries reduce blood flow to the heart muscle, leading to weakened contractions. - Hypertension (high blood pressure): Over time, high blood pressure forces the heart to work harder, leading to muscle weakening. - Cardiomyopathy: Diseases that affect the heart muscle can reduce its pumping ability. - Heart valve diseases: Improperly functioning heart valves can make the heart work harder and weaken over time. - Arrhythmias: Abnormal heart rhythms can make the heart less efficient.

Symptoms

Patients with chronic systolic CHF may experience the following symptoms: - Shortness of breath (especially during exertion or while lying down) - Fatigue and weakness - Swelling in the legs, ankles, and feet - Rapid or irregular heartbeat - Persistent cough or wheezing with white or pink-tinged phlegm - Difficulty concentrating

Diagnosis

To diagnose chronic systolic CHF, doctors use several tests, including: - Echocardiogram: Measures the ejection fraction (a percentage that indicates how well the heart is pumping). An ejection fraction of ≤40% suggests systolic heart failure. - Electrocardiogram (ECG): Identifies abnormal rhythms or past heart attacks. - Chest X-ray: Detects fluid buildup in the lungs. - B-type natriuretic peptide (BNP) test: Measures a hormone that rises when heart failure is present. - Cardiac MRI or CT scan: Provides detailed images of the heart’s size and function.

Treatment Principles

Management of systolic CHF involves a combination of lifestyle changes, medications, and sometimes procedures or devices.

1. Lifestyle Modifications

  • Reduce salt intake to prevent fluid retention.
  • Maintain a healthy weight.
  • Engage in regular physical activity as advised by a doctor.
  • Quit smoking and limit alcohol intake.
  • Monitor daily fluid intake to avoid overloading the heart.

2. Medications

Several classes of medications are used to manage systolic CHF: - ACE inhibitors or ARBs: Help open up blood vessels, making it easier for the heart to pump. - Beta-blockers: Slow down the heart rate and reduce strain on the heart. - Diuretics: Help remove excess fluid from the body, reducing swelling and shortness of breath. - Aldosterone antagonists: Help prevent sodium retention and further heart damage. - SGLT2 inhibitors: Originally designed for diabetes but shown to improve heart failure outcomes.

3. Advanced Treatments

For severe cases, additional treatments may be necessary: - Implantable cardioverter-defibrillator (ICD): Prevents life-threatening arrhythmias. - Cardiac resynchronization therapy (CRT): Helps coordinate the heartbeat. - Heart transplant or ventricular assist devices (VADs): Used in end-stage heart failure.

Conclusion

Chronic systolic CHF is a serious but manageable condition. Early diagnosis and proper treatment can improve quality of life and prevent complications. Patients should work closely with their healthcare team to manage symptoms effectively.

Source recommendations

1. American Heart Association Guidelines on Heart Failure

  1. https://www.ahajournals.org/doi/10.1161/CIR.0000000000001063
  2. https://www.heart.org/en/health-topics/heart-failure
  3. https://professional.heart.org/en/guidelines-and-statements
  4. https://www.heart.org/en/professional/quality-improvement/get-with-the-guidelines/get-with-the-guidelines-heart-failure
  5. https://professional.heart.org/en/science-news/-/media/832EA0F4E73948848612F228F7FA2D35.ashx

2. European Society of Cardiology Guidelines on Heart Failure

  1. https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/Acute-and-Chronic-Heart-Failure
  2. https://academic.oup.com/eurheartj/article/42/36/3599/6358045
  3. https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/Focused-Update-on-Heart-Failure-Guidelines
  4. https://academic.oup.com/eurheartj/article/44/37/3627/7246292
  5. https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines

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