Drugs for Heart Arrhythmia

Introduction

Heart arrhythmia refers to an abnormal heart rhythm, which can be too fast (tachycardia), too slow (bradycardia), or irregular. To manage arrhythmia, cardiologists often prescribe specific medications that regulate electrical impulses in the heart.

Main Classes of Antiarrhythmic Drugs

1. Sodium Channel Blockers (Class I)

These drugs slow down the conduction of electrical signals in the heart. - Examples: Quinidine, Procainamide, Lidocaine, Flecainide - Uses: Ventricular and supraventricular arrhythmias - Side effects: Dizziness, nausea, cardiac conduction issues

2. Beta-Blockers (Class II)

These reduce heart rate and control stress-related arrhythmias. - Examples: Metoprolol, Atenolol, Propranolol - Uses: Atrial fibrillation, supraventricular tachycardia - Side effects: Fatigue, low blood pressure, dizziness

3. Potassium Channel Blockers (Class III)

These prolong the electrical phase of heartbeats. - Examples: Amiodarone, Sotalol, Dofetilide - Uses: Atrial fibrillation, life-threatening ventricular arrhythmias - Side effects: Thyroid issues (amiodarone), lung toxicity, QT prolongation

4. Calcium Channel Blockers (Class IV)

These slow conduction in the heart’s electrical system. - Examples: Verapamil, Diltiazem - Uses: Atrial fibrillation, supraventricular tachycardia - Side effects: Low blood pressure, constipation, dizziness

5. Other Medications

  • Digoxin: Strengthens heart contractions and slows heart rate.
  • Anticoagulants (e.g., Warfarin, NOACs): Prevent blood clots in atrial fibrillation.

Conclusion

The choice of medication depends on the type of arrhythmia, underlying heart conditions, and possible drug interactions. It’s essential to follow your cardiologist’s recommendations and undergo regular monitoring.

Source recommendations

1. American Heart Association Guidelines

  1. https://professional.heart.org/en/guidelines-and-statements
  2. https://www.heart.org/
  3. https://professional.heart.org/en/guidelines-statements
  4. https://cpr.heart.org/en/resuscitation-science/cpr-and-ecc-guidelines
  5. https://www.heart.org/en/healthy-living/fitness/fitness-basics/aha-recs-for-physical-activity-in-adults

2. European Society of Cardiology Guidelines

  1. https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines
  2. https://academic.oup.com/eurheartj/article/42/34/3227/6358713
  3. https://www.escardio.org/Guidelines
  4. https://academic.oup.com/eurheartj/article/44/39/4043/7238227
  5. https://www.escardio.org/

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