Inferior Wall Myocardial Infarction (IWMI) on ECG

Introduction

Inferior Wall Myocardial Infarction (IWMI) refers to a heart attack involving the inferior (lower) part of the heart, typically supplied by the right coronary artery (RCA) or, in some cases, the left circumflex artery (LCx). ECG plays a crucial role in its diagnosis.

ECG Changes in IWMI

Key Features:

  1. ST-segment Elevation:
    • Found in leads II, III, and aVF, confirming myocardial injury in the inferior wall.
  2. Reciprocal ST-segment Depression:
    • Typically seen in leads I and aVL, indicating ischemic changes in the opposing regions.
  3. Additional Considerations:
    • Right Ventricular Involvement: If the RCA is affected proximally, ST elevation might be present in lead V1 or V4R (right-sided ECG leads).
    • Posterior Involvement: ST depression in V1-V3 suggests a posterior infarction, often requiring confirmation with posterior leads (V7-V9).

Clinical Importance

  • Bradycardia and Hypotension Risk: As the RCA often supplies the sinoatrial (SA) and atrioventricular (AV) nodes, patients might develop bradycardia or even heart block.
  • Treatment Considerations:
    • Avoid nitroglycerin in patients with suspected right ventricular infarction, as it can worsen hypotension.
    • Fluid resuscitation may be needed if there is significant hypotension due to RV infarction.
    • Reperfusion therapy (PCI or fibrinolysis) should be initiated promptly.

Conclusion

Timely recognition of IWMI using ECG is critical for appropriate management. Understanding the ECG changes and potential complications can help guide immediate treatment and improve patient outcomes.

Source recommendations

1. American Heart Association Guidelines for the Management of ST-Elevation Myocardial Infarction

  1. https://professional.heart.org/en/science-news/2021-acc-aha-scai-guideline-for-coronary-artery-revascularization
  2. https://www.ahajournals.org/doi/10.1161/cir.0b013e3182742cf6
  3. https://pubmed.ncbi.nlm.nih.gov/23256914/
  4. https://www.ahajournals.org/doi/10.1161/01.cir.0000134791.68010.fa
  5. https://www.sciencedirect.com/science/article/pii/S073510972106157X

2. European Society of Cardiology Guidelines for the Management of Acute Coronary Syndromes in Patients Presenting with ST-Segment Elevation

  1. https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/Acute-Coronary-Syndromes-ACS-Guidelines
  2. https://pubmed.ncbi.nlm.nih.gov/21873419/
  3. https://academic.oup.com/eurheartj/article/42/14/1289/5898842
  4. https://pubmed.ncbi.nlm.nih.gov/26320110/
  5. https://academic.oup.com/eurheartj/article/39/2/119/4095042

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