Laboratory Tests for Heart Function

Introduction

The heart is a vital organ responsible for pumping blood throughout the body. Assessing its function is crucial in diagnosing and managing cardiovascular diseases. Doctors often use laboratory tests to evaluate heart health, detect damage, and monitor treatment effectiveness.

Key Laboratory Tests

1. Troponin (Troponin I and Troponin T)

  • Purpose: Detects heart muscle damage, primarily in heart attacks.
  • Significance: Even small elevations indicate potential cardiac injury.

2. Creatine Kinase-MB (CK-MB)

  • Purpose: Helps diagnose heart attacks; CK-MB is an enzyme found in heart muscle cells.
  • Significance: Elevated levels indicate heart muscle injury but can also rise due to skeletal muscle damage.

3. Brain Natriuretic Peptide (BNP) & N-terminal proBNP (NT-proBNP)

  • Purpose: Assesses heart failure severity.
  • Significance: Higher levels suggest worsening heart failure.

4. C-reactive Protein (CRP) and High-sensitivity CRP (hs-CRP)

  • Purpose: Measures inflammation in the body, which contributes to heart disease.
  • Significance: Elevated levels are linked to increased cardiovascular risk.

5. Lipid Profile (Cholesterol Tests)

  • Components:
    • Total cholesterol
    • Low-density lipoprotein (LDL) – “bad” cholesterol
    • High-density lipoprotein (HDL) – “good” cholesterol
    • Triglycerides
  • Purpose: Assesses risk for atherosclerosis and heart disease.

6. Electrolytes (Sodium, Potassium, Magnesium, Calcium)

  • Purpose: Imbalances in electrolytes can lead to arrhythmias and other heart issues.

7. Blood Sugar (Glucose) and Hemoglobin A1c (HbA1c)

  • Purpose: Assesses diabetes risk, which is a major factor in heart disease.

8. D-dimer

  • Purpose: Helps diagnose blood clots, which can lead to heart attacks or pulmonary embolisms.

9. Liver and Kidney Function Tests

  • Purpose: The liver and kidneys play roles in heart health; dysfunction can aggravate cardiac conditions.

Conclusion

Laboratory tests provide essential insights into heart health, helping in the early detection and management of cardiac diseases. Your doctor will determine which tests are necessary based on symptoms, risk factors, and medical history.

Source recommendations

1. American Heart Association Guidelines

  1. https://professional.heart.org/en/guidelines-and-statements
  2. https://www.heart.org/
  3. https://professional.heart.org/en/guidelines-statements
  4. https://cpr.heart.org/en/resuscitation-science/cpr-and-ecc-guidelines
  5. https://www.heart.org/en/healthy-living/fitness/fitness-basics/aha-recs-for-physical-activity-in-adults

2. European Society of Cardiology Guidelines

  1. https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines
  2. https://academic.oup.com/eurheartj/article/42/34/3227/6358713
  3. https://www.escardio.org/Guidelines
  4. https://academic.oup.com/eurheartj/article/44/39/4043/7238227
  5. https://www.escardio.org/

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