Myocardial Viability Scan: What You Need to Know

Introduction

A myocardial viability scan is a diagnostic test used to determine whether heart muscle that has been damaged (for example, due to a heart attack) still has living cells that could recover function if blood flow is restored. This is particularly important in patients with coronary artery disease (CAD) and heart failure, as it helps doctors decide whether procedures like bypass surgery or angioplasty might improve heart function.

Why is Myocardial Viability Important?

When heart muscle is deprived of oxygen due to blocked arteries, it can either: 1. Die (infarcted tissue) – This tissue is permanently damaged and cannot recover. 2. Go into hibernation – The muscle is still alive but has reduced function because of insufficient blood supply. 3. Be stunned – Temporary dysfunction after blood supply has been restored.

If a significant portion of heart muscle is viable, restoring blood flow may improve heart function and prevent heart failure progression.

Methods for Assessing Myocardial Viability

Several imaging techniques are used to evaluate myocardial viability:

1. Positron Emission Tomography (PET) Scan

  • Uses fluorodeoxyglucose (FDG-PET) to differentiate viable from non-viable myocardium.
  • Gold standard for viability assessment.

2. Cardiac Magnetic Resonance Imaging (CMR) with Late Gadolinium Enhancement (LGE)

  • Shows scar tissue vs. viable myocardium.
  • Helps assess the extent of myocardial damage.

3. Dobutamine Stress Echocardiography (DSE)

  • Uses low-dose dobutamine to see if weakened heart muscle improves with stimulation.

4. Single Photon Emission Computed Tomography (SPECT) Scan

  • Uses radioactive tracers (e.g., thallium-201 or technetium-99m) to assess blood flow and viability.

When is a Myocardial Viability Scan Recommended?

  • Chronic heart failure with reduced ejection fraction (HFrEF) where revascularization is considered.
  • Patients after a heart attack to assess if damaged areas can recover.
  • Severe coronary artery disease (CAD) with reduced heart function.
  • Before deciding on bypass surgery (CABG) or angioplasty in patients with heart failure to determine benefit.

Conclusion

A myocardial viability scan is a crucial tool in modern cardiology. It helps determine whether restoring blood flow to damaged heart muscle can improve heart function and guide treatment options. Doctors use different imaging methods (PET, MRI, echocardiography, and SPECT) based on clinical scenarios. If you or a loved one have heart failure or CAD, discussing myocardial viability testing with your cardiologist may help tailor the best treatment plan.

Source recommendations

1. American College of Cardiology/American Heart Association Guidelines for the Management of Patients with Chronic Coronary Artery Disease

  1. https://www.ahajournals.org/doi/10.1161/CIR.0000000000001168
  2. https://pubmed.ncbi.nlm.nih.gov/37471501/
  3. https://www.jacc.org/guidelines/chronic-coronary-disease
  4. https://www.acc.org/Guidelines/Hubs/Chronic-Coronary-Disease
  5. https://professional.heart.org/en/science-news/2023-guideline-for-the-management-of-patients-with-chronic-coronary-disease

2. European Society of Cardiology Guidelines on Myocardial Revascularization

  1. https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/ESC-EACTS-Guidelines-in-Myocardial-Revascularisation-Guidelines-for
  2. https://academic.oup.com/eurheartj/article/40/2/87/5079120
  3. https://pubmed.ncbi.nlm.nih.gov/30165437/
  4. https://academic.oup.com/eurheartj/article/35/37/2541/581070
  5. https://pubmed.ncbi.nlm.nih.gov/25173339/

3. American Society of Nuclear Cardiology Practice Guidelines for the Clinical Use of Cardiac Radionuclide Imaging

  1. https://pubmed.ncbi.nlm.nih.gov/14522503/
  2. https://www.ahajournals.org/doi/10.1161/01.cir.0000080946.42225.4d
  3. https://www.jacc.org/doi/abs/10.1016/j.jacc.2003.08.011
  4. https://www.asnc.org/clinical-guidelines-tools/
  5. https://www.jtcvs.org/article/S0022-5223(18)33502-5/fulltext

Our advantages:

patient2376100
Best practices from USA, EU and Japan
Our answers to your questions are based on the clinical recommendations of countries with the most developed healthcare systems in the field of cardiology in the USA, the EU and Japan.
prescription18648039
Always up-to-date information
On a daily basis, we monitor for you all new scientific research publications in leading scientific journals on medical issues of interest to you.
We monitor all innovations and changes in the field of cardiac disease treatment on a daily basis.
fvfflf7q
Get second opinion
Here you can learn everything that even your doctor may not know about cardiology (if he does not speak English and he does not read 117 leading medical journals on cardiology every month).
1xr4duup
The most comprehensive and up-to-date collection of free cardiology materials
Our website contains the most comprehensive and up-to-date collection of free cardiology materials in your country.
Every 3-5 years, half of the scientific approaches to treatment in the field of cardiology are reviewed as a result of specialized scientific discoveries. With us, you don't have to wait these years to learn about the best ways to treat you and your loved ones.
arrow
Please register in order to receive information regarding possible complications and new approaches to treatment of cardiovascular diseases via email in our Newsletters.
arrow