Heart Valves: Structure, Function, and Common Diseases

Introduction

Heart valves are essential structures in the cardiovascular system, ensuring that blood flows in the correct direction through the heart chambers. There are four heart valves: - Aortic Valve: Controls blood flow from the left ventricle to the aorta. - Mitral Valve: Regulates blood flow between the left atrium and left ventricle. - Tricuspid Valve: Controls flow from the right atrium to the right ventricle. - Pulmonary Valve: Directs blood from the right ventricle to the pulmonary artery.

Common Valve Disorders

1. Stenosis

  • Occurs when the valve does not open fully, restricting blood flow.
  • Common causes: Rheumatic heart disease, congenital defects, and calcification.
  • Symptoms: Shortness of breath, chest pain, fatigue, dizziness.

2. Regurgitation (Insufficiency)

  • Occurs when the valve does not close properly, allowing backflow of blood.
  • Causes: Valve prolapse, infections (endocarditis), or damage from a heart attack.
  • Symptoms: Fatigue, palpitations, swelling in the legs, shortness of breath.

3. Prolapse

  • Seen most commonly in the mitral valve (mitral valve prolapse, MVP).
  • Causes: Genetic conditions, connective tissue disorders.
  • Symptoms: Often asymptomatic, but can include palpitations, chest pain, and dizziness.

Diagnosis

  • Echocardiography (ultrasound of the heart) is the gold standard.
  • Additional tests: Electrocardiogram (ECG), cardiac MRI, cardiac catheterization.

Treatment Options

  • Medications: Beta-blockers, diuretics, anticoagulants to manage symptoms.
  • Interventions:
    • Valve repair (e.g., mitral valve clip for regurgitation).
    • Valve replacement (mechanical or biological prostheses).
    • Balloon valvuloplasty (for some stenotic valves).

Conclusion

Valve diseases can significantly impact heart function but are manageable with proper diagnosis and treatment. Lifestyle modifications, medical therapy, and surgical options help restore normal heart function and improve quality of life.

Source recommendations

1. 2021 ESC/EACTS Guidelines for the Management of Valvular Heart Disease

  1. https://academic.oup.com/eurheartj/article/43/7/561/6358470
  2. https://pubmed.ncbi.nlm.nih.gov/34453165/
  3. https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/Valvular-Heart-Disease-Guidelines
  4. https://www.jacc.org/doi/10.1016/j.jacc.2023.05.061
  5. https://www.sciencedirect.com/science/article/pii/S0735109723059739

2. 2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease

  1. https://www.ahajournals.org/doi/10.1161/CIR.0000000000000923
  2. https://pubmed.ncbi.nlm.nih.gov/33332149/
  3. https://www.acc.org/Latest-in-Cardiology/ten-points-to-remember/2020/12/16/21/58/2020-ACC-AHA-VHD-GL-Pt-1-GL-VHD
  4. https://www.sciencedirect.com/science/article/pii/S073510972037902X
  5. https://professional.heart.org/en/science-news/2020-acc-aha-guideline-for-the-management-of-patients-with-valvular-heart-disease

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