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Understanding Polymorphic Ventricular Tachycardia (VT) on ECG
Introduction
Polymorphic Ventricular Tachycardia (VT) is a life-threatening arrhythmia characterized by a rapid heart rate with continuously changing QRS complex morphology. It can lead to syncope (fainting) or sudden cardiac arrest if not promptly managed.
ECG Characteristics
- Irregular QRS Morphology: The hallmark of polymorphic VT is that the QRS complexes vary in shape and size from beat to beat.
- Rapid Ventricular Rate: Typically, the ventricular rate exceeds 150 beats per minute.
- Torsades de Pointes (TdP) Variant: If polymorphic VT occurs in the presence of a prolonged QT interval on a baseline ECG, it is called Torsades de Pointes and requires special treatment.
Causes of Polymorphic VT
Several conditions can predispose someone to polymorphic VT, including: - Electrolyte Imbalances (low potassium, magnesium, or calcium) - Ischemic Heart Disease (e.g., myocardial infarction) - Congenital Long QT Syndrome - Drug-Induced QT Prolongation (e.g., antiarrhythmic drugs, certain antibiotics, and antipsychotics) - Catecholaminergic Polymorphic VT (CPVT) (genetic disorder)
Management and Treatment
- Immediate Defibrillation: If the patient is unstable, electrical cardioversion or defibrillation is required.
- Magnesium Sulfate: The first-line treatment for Torsades de Pointes.
- Correction of Electrolyte Imbalances: Potassium and magnesium supplementation.
- Withdrawal of QT-Prolonging Drugs: Essential in cases of drug-induced QT prolongation.
- Beta-Blockers: Used in cases of CPVT to reduce arrhythmic episodes.
- ICD Placement: An implantable cardioverter defibrillator (ICD) may be needed for high-risk patients.
Conclusion
Recognizing polymorphic VT on ECG and identifying the underlying cause is crucial for effective treatment. Early intervention can prevent life-threatening complications like sudden cardiac death.
Source recommendations
1. 2022 ESC Guidelines on Ventricular Arrhythmias and Sudden Cardiac Death
- https://academic.oup.com/eurheartj/article/43/40/3997/6675633
- https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/Ventricular-Arrhythmias-and-the-Prevention-of-Sudden-Cardiac-Death
- https://pubmed.ncbi.nlm.nih.gov/36017572/
- https://www.acc.org/Latest-in-Cardiology/ten-points-to-remember/2022/09/02/14/23/2022-ESC-Guidelines-for-VAs-ESC-2022
- https://pubmed.ncbi.nlm.nih.gov/26320108/
2. ACC/AHA/HRS Guideline for the Evaluation and Management of Patients with Ventricular Arrhythmias
- https://www.ahajournals.org/doi/10.1161/CIR.0000000000000549
- https://www.hrsonline.org/guidance/clinical-resources/2017-accahahrs-guideline-evaluation-and-management-patients-syncope
- https://www.ahajournals.org/doi/10.1161/cir.0000000000000499
- https://pubmed.ncbi.nlm.nih.gov/29097320/
- https://www.jacc.org/doi/10.1016/j.jacc.2017.03.003
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If you or your loved ones experience any of these symptoms, you should consult a doctor in time. Remember that self-medication can be dangerous, and timely diagnosis will preserve the quality and life expectancy.
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