Premature Ventricular Contractions (PVCs): Causes and Risk Factors

Introduction

Premature Ventricular Contractions (PVCs) are early heartbeats originating in the ventricles. They can be benign or indicate an underlying heart condition. Understanding their causes and triggers is essential for effective management.

Common Causes of PVCs

1. Structural Heart Disease:

  • Myocardial infarction (heart attack)
  • Cardiomyopathy
  • Heart failure
  • Valvular heart disease

2. Electrolyte Imbalances:

  • Low potassium (hypokalemia)
  • Low magnesium (hypomagnesemia)
  • Low calcium (hypocalcemia)

3. Increased Sympathetic Nervous Activity:

  • Stress and anxiety
  • Excessive caffeine or stimulant use
  • Sleep deprivation

4. Medications and Substances:

  • Decongestants and cold medications
  • Antiarrhythmic drugs (paradoxical effect)
  • Alcohol and recreational drugs (e.g., cocaine, amphetamines)

5. Underlying Medical Conditions:

  • Hyperthyroidism
  • Chronic lung diseases (e.g., COPD)
  • Anemia

When to Seek Medical Attention?

If PVCs occur frequently, cause symptoms like dizziness, chest pain, or fainting, or are associated with heart disease, medical evaluation is necessary. A cardiologist may recommend ECG, Holter monitoring, or an echocardiogram to assess the condition further.

Conclusion

While occasional PVCs can be harmless, frequent or symptomatic PVCs may require further evaluation and lifestyle modifications. If you experience frequent palpitations, consult a cardiologist for a thorough assessment.

Source recommendations

1. American Heart Association Guidelines on Arrhythmias

  1. https://www.heart.org/en/health-topics/arrhythmia
  2. https://www.ahajournals.org/doi/10.1161/CIR.0000000000001193
  3. https://www.heart.org/en/health-topics/arrhythmia/about-arrhythmia
  4. https://www.ahajournals.org/doi/10.1161/CIR.0000000000000549
  5. https://pubmed.ncbi.nlm.nih.gov/29084733/

2. European Society of Cardiology Guidelines on Ventricular Arrhythmias and Sudden Cardiac Death

  1. https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/Ventricular-Arrhythmias-and-the-Prevention-of-Sudden-Cardiac-Death
  2. https://academic.oup.com/eurheartj/article/43/40/3997/6675633
  3. https://www.ahajournals.org/doi/10.1161/CIR.0000000000000549
  4. https://pubmed.ncbi.nlm.nih.gov/36017572/
  5. https://www.sciencedirect.com/science/article/pii/S2405500X22010945

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