Premature Ventricular Contractions (PVCs) and ECG Interpretation

Introduction

Premature Ventricular Contractions (PVCs) are early heartbeats originating from the ventricles. They are commonly seen on an electrocardiogram (ECG) and may be benign or indicate an underlying heart condition.

ECG Characteristics of PVCs

  • Early QRS Complex: The PVC appears earlier than expected in the normal rhythm.
  • Wide QRS Complex: Due to abnormal conduction through ventricular myocardium.
  • No Preceding P Wave: The beat originates in the ventricles, bypassing the normal atrial conduction.
  • Compensatory Pause: Often a PVC is followed by a compensatory pause before the next regular beat.
  • Unifocal vs. Multifocal PVCs: If PVCs have the same morphology, they come from one site (unifocal). If they have different shapes, multiple ventricular foci may be present (multifocal).

Causes and Risk Factors

  • Benign Causes: Caffeine, stress, lack of sleep, electrolyte imbalances.
  • Cardiac Causes: Coronary artery disease, heart failure, structural abnormalities.
  • Systemic Causes: Hyperthyroidism, anemia, medications.

When to Be Concerned

  • Frequent PVCs (>10% of total beats).
  • PVCs in a Pattern (bigeminy, trigeminy, couplets).
  • Associated with Symptoms (dizziness, syncope, chest pain).
  • Underlying Heart Disease (history of myocardial infarction, cardiomyopathy).

Diagnostic Workup

  • ECG Monitoring: 12-lead ECG, Holter or event monitor.
  • Echocardiography: Assess heart structure and function.
  • Stress Test: Evaluate PVCs under physical stress.
  • Electrophysiology Study: In high-risk cases.

Treatment Options

Lifestyle Modifications

  • Reduce caffeine, alcohol, and stress.
  • Ensure balanced electrolytes (magnesium, potassium).
  • Improve sleep and exercise regularly.

Medical Therapy

  • Beta-blockers: First-line for symptomatic PVCs.
  • Calcium Channel Blockers: Alternative options.
  • Antiarrhythmic Drugs: Only in refractory cases due to risks.

Interventional Approaches

  • Catheter Ablation: If PVC burden is high and symptoms persist.

Conclusion

PVCs are common and often benign but require evaluation if they occur frequently or cause symptoms. An ECG is crucial to detection, and further workup depends on risk factors. Consult a cardiologist if PVCs are persistent or symptomatic.

Source recommendations

1. American Heart Association (AHA) Guidelines on Ventricular Arrhythmias

  1. https://www.ahajournals.org/doi/10.1161/CIR.0000000000000549
  2. https://www.heart.org/en/health-topics/arrhythmia/about-arrhythmia/tachycardia--fast-heart-rate
  3. https://www.ahajournals.org/doi/10.1161/CIR.0000000000001193
  4. https://www.heart.org/en/health-topics/arrhythmia/about-arrhythmia/ventricular-fibrillation
  5. https://www.sciencedirect.com/science/article/pii/S2405500X22010945

2. European Society of Cardiology (ESC) Guidelines for the Management of Ventricular Arrhythmias

  1. https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/Ventricular-Arrhythmias-and-the-Prevention-of-Sudden-Cardiac-Death
  2. https://academic.oup.com/eurheartj/article/43/40/3997/6675633
  3. https://pubmed.ncbi.nlm.nih.gov/36017572/
  4. https://www.sciencedirect.com/science/article/pii/S2405500X22010945
  5. https://pubmed.ncbi.nlm.nih.gov/26320108/

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