Right Heart Failure: Causes, Symptoms, and Treatment

Introduction

Right heart failure (RHF) occurs when the right ventricle of the heart cannot pump blood efficiently into the lungs. This causes blood to back up in the veins, leading to fluid retention and swelling in the lower limbs, liver, and abdomen.

Causes of Right Heart Failure

RHF is often a consequence of left-sided heart failure, but it can also result from other conditions, including: - Pulmonary Hypertension: Increased pressure in the lung arteries makes it harder for the right ventricle to pump blood. - Chronic Lung Diseases (Cor Pulmonale): Conditions like COPD or pulmonary fibrosis increase lung resistance. - Congenital Heart Diseases: Malformations present from birth can overload the right ventricle. - Pulmonary Embolism: A blood clot in the lungs can suddenly increase the burden on the right heart. - Myocardial Infarction: A heart attack affecting the right ventricle can reduce its function.

Symptoms of Right Heart Failure

  • Swelling in the legs, ankles, and abdomen (edema)
  • Increased jugular venous pressure (visible neck vein swelling)
  • Fatigue and weakness
  • Shortness of breath, especially during exertion
  • Abdominal discomfort due to liver congestion

Diagnosis

Doctors use a combination of tests to diagnose RHF: - Echocardiography: Assesses heart function and pressures. - Electrocardiogram (ECG): Identifies strain or damage to the heart muscle. - Chest X-ray: Shows lung congestion and heart size. - Cardiac MRI or CT Scan: Provides detailed heart images. - Right Heart Catheterization: Measures pulmonary artery pressures, confirming pulmonary hypertension.

Treatment Approaches

Treatment depends on the underlying cause:

1. Managing Fluid Retention

  • Diuretics: Reduce swelling and fluid overload.
  • Sodium Restriction: Limits fluid buildup.

2. Enhancing Right Ventricular Function

  • Oxygen Therapy (if hypoxia is present)
  • Pulmonary Vasodilators for patients with pulmonary hypertension
  • Inotropic Support (e.g., dobutamine) in severe cases

3. Treating the Underlying Condition

  • Pulmonary Embolism → Anticoagulation Therapy
  • Chronic Lung Disease → Optimal COPD/Asthma management
  • Heart Failure with Reduced Ejection Fraction → Beta-blockers, ACE inhibitors, or ARNi

4. Surgical and Device-Based Interventions

  • Heart Transplantation (in end-stage cases)
  • Implantable Cardioverter-Defibrillators (ICD) for arrhythmia prevention
  • Pulmonary Endarterectomy (in selected cases of chronic thromboembolic pulmonary hypertension)

Prognosis and Lifestyle Modifications

  • Regular exercise adapted to tolerance
  • Healthy diet with controlled salt intake
  • Avoidance of tobacco and alcohol
  • Close monitoring of body weight and fluid status

Conclusion

Right heart failure is a serious condition, but with appropriate treatment and lifestyle changes, many patients can maintain a good quality of life. Early diagnosis and management of underlying conditions are key to preventing progression.

Source recommendations

1. American College of Cardiology/American Heart Association Heart Failure Guidelines

  1. https://www.ahajournals.org/doi/10.1161/CIR.0000000000001063
  2. https://www.acc.org/Guidelines
  3. https://www.jacc.org/doi/10.1016/j.jacc.2023.12.024
  4. https://www.acc.org/education-and-meetings/products-and-resources/features/global-cv-institute/heart-failure-guidelines
  5. https://professional.heart.org/en/science-news/-/media/832EA0F4E73948848612F228F7FA2D35.ashx

2. European Society of Cardiology Heart Failure Guidelines

  1. https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/Acute-and-Chronic-Heart-Failure
  2. https://academic.oup.com/eurheartj/article/42/36/3599/6358045
  3. https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/Focused-Update-on-Heart-Failure-Guidelines
  4. https://academic.oup.com/eurheartj/article/44/37/3627/7246292
  5. https://pubmed.ncbi.nlm.nih.gov/21159794/

3. Pulmonary Hypertension Guidelines (ESC/ERS)

  1. https://academic.oup.com/eurheartj/article/43/38/3618/6673929
  2. https://publications.ersnet.org/content/erj/early/2022/08/25/1399300300879-2022.abstract
  3. https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/Pulmonary-Hypertension-Guidelines-on-Diagnosis-and-Treatment-of
  4. https://pubmed.ncbi.nlm.nih.gov/36017548/
  5. https://www.acc.org/Latest-in-Cardiology/ten-points-to-remember/2022/08/30/19/11/2022-ESC-Guidelines-for-Pulmonary-Hypertension-ESC-2022

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