Sinus Bradycardia on ECG: Meaning, Causes, and Clinical Significance

Introduction

Sinus bradycardia is a condition where the heart rate is lower than 60 beats per minute (bpm) due to slower activity of the sinus node, the natural pacemaker of the heart. It can be a normal finding in well-trained athletes or occur as a result of medical conditions.

How Does Sinus Bradycardia Appear on an ECG?

An electrocardiogram (ECG) of sinus bradycardia typically shows: - Regular P waves before every QRS complex, confirming sinus rhythm. - Prolonged R-R intervals , meaning the heart beats slower than normal. - Normal P-QRS-T sequence , without abnormal conduction disturbances.

Causes of Sinus Bradycardia

Sinus bradycardia can be caused by: 1. Physiological Causes: - Athletes with high vagal tone - During sleep 2. Pathological Causes: - Hypothyroidism - Electrolyte imbalances (e.g., high potassium levels) - Sinus node dysfunction (sick sinus syndrome) - Certain medications (beta-blockers, calcium channel blockers, digoxin) - Myocardial infarction (especially inferior wall MI affecting the sinus node) 3. Autonomic Nervous System Disorders: - Vasovagal syncope - Neurogenic causes (e.g., increased vagal tone)

Clinical Significance and When to Seek Medical Attention

  • Asymptomatic: Common in athletes and usually harmless.
  • Symptomatic Cases: May involve dizziness, fatigue, syncope (fainting), and reduced exercise tolerance.
  • Severe Bradycardia (<40 bpm) or Persistent Symptoms: May warrant further evaluation, including Holter monitoring or electrophysiological studies.
  • Management:
    • Correction of underlying causes (e.g., adjusting medication doses, treating hypothyroidism).
    • Pacemaker implantation may be required in severe cases with symptomatic bradycardia (e.g., sick sinus syndrome).

Conclusion

Sinus bradycardia is often a benign condition but may indicate significant underlying heart or systemic disease if symptomatic. Recognition on ECG and correlation with clinical findings are essential for appropriate management.

Source recommendations

1. 2023 European Society of Cardiology (ESC) Guidelines for the Management of Bradyarrhythmias

  1. https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines
  2. https://academic.oup.com/eurheartj/article/44/37/3503/7246608
  3. https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/CVD-and-Diabetes-Guidelines
  4. https://www.heartrhythmjournal.com/article/S1547-5271(23)02246-4/fulltext
  5. https://pubmed.ncbi.nlm.nih.gov/36017572/

2. American College of Cardiology (ACC)/American Heart Association (AHA)/Heart Rhythm Society (HRS) 2018 Guidelines on Bradycardia and Conduction Delay

  1. https://www.ahajournals.org/doi/10.1161/CIR.0000000000000628
  2. https://pubmed.ncbi.nlm.nih.gov/30412710/
  3. https://www.acc.org/latest-in-cardiology/ten-points-to-remember/2018/11/05/15/12/2018-acc-aha-hrs-guideline-on-bradycardia
  4. https://pubmed.ncbi.nlm.nih.gov/30586772/
  5. https://www.hrsonline.org/guidance/clinical-resources/2018-accahahrs-guideline-evaluation-and-management-patients-bradycardia-and-cardiac-conduction

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